Be the change you want to see in the world! We’re at the beginning of greatness here, the tip of a drill that will pierce the fediverse, carving out a meme that future generations will never see the bottom of!
It wouldn’t be the heat used for drying, it would be the heat used for washing. Assuming that you have a dishwasher with a sanitize cycle/option always use it. they are required to reach a minimum temperature of 150f. typical range in actual products is 165ºF to 180ºF (74ºC to 82ºC)
I still wouldn’t trust that to be all that great. Sanitize isn’t a very controlled term (sterilize is). If you look up autoclaves, which are essentially steam baths to kill bacteria, they only get 90% of microbial life after more than an hour, and their temperatures are much higher than any dishwasher will reach.
The only time I’ve seen something like this is when my doctor really wanted me to try an anti-depressant, so he gave me a perpetual supply of free samples.
It depends on what you mean by “start working.” The first time I took a sertraline, I felt absolutely baked, but I feel like it took weeks for the desirable effects to take hold.
Then again, my doctor also told me that something like 60% of the effects are a placebo.
Regardless, yes, he would give me like a month of these individal samples at a time. I’m not sure how he swung that. It was like 2003 or 2004.
For classical antidepressants Chemicals tend to function pretty fast but the effect is designed to be subtle because you need to live a normal life, capable of dealing with and feeling both ups and downs. not be perpetually smiling or brain dead.
After some time “a few weeks” of taking a daily dose your body and mind adjust to the subtle changes causing a stable therapeutic effect. At least thats what I understand is the idea.
But lately there is also sm of a psychedelic renaissance of medicine and they work entirely different where a single dose within a therapeutic setting creates a longer lasting feeling of increased well being.
Nasal Ketamine seems to receive allot of attention, near instantly improving the condition. They tend to need 1 dose every 5 weeks so its less addictive then classic medicine. But i do admit it instant improvement for treatment resistant medications is a bold claim and still subject of more research.
The side effects can last for weeks. It’s like a really shitty onboarding process. For some, the side effects are not bad. Personally I can say that the first 2 to 4 weeks are usually filled with nausea, extreme fatigue and exhaustion.
The way that these sorts of meds have been described to me is that “they give you a leg up”, meaning it gives you just enough of a “boost” that you might actually follow through on therapy and the strategies it offers.
It has been years now, and still no luck. I’d love to live a normal life, whatever the fuck that means lol
A doctor said this and it was such a good metaphor: imagine that you have a 3000 year old machine (which no one understands anymore) with a bunch of cogs and gears, and you’re looking down at it from above. You’re trying to fix a gear that is slightly out of alignment further down in the machine, you can’t really tell which one it is but you know roughly which area, and to fix it you drop a rock into the machine and watch it fall down.
That’s what we’re doing with SSRIs. We’re dropping a rock that manipulates our serotonin, which gives a bunch of effects but not the one we’re after. The one we’re after is somewhere down the line. It’s affected by processes that are affected by the serotonin somehow. We’re not exactly sure which one it is, but we know that if we drop the rock in there it will make the gears align sooner or later.
Which is why it takes time, and why it has some odd effects on people sometimes.
edit: added a detail I missed, to make it clearer.
That’s a good metaphor! I’m not sure about the rock though, throwing a rock into a complicated machine doesn’t seem like the best idea. I’d consider replacing it with oil, where it needs to cover the gears at the top first before it can drip down.
Yes! That’s the point of the metaphor! The SSRI is the rock. We’re not exactly sure how it’s gonna land, or what it’s total effects are on the machine, but it’s the tool we have and it’s the one we’re using. I don’t remember where I heard it, but I instantly understood why I became so paranoid all those years ago when I tried antidepressants.
edit: and that doesn’t mean that a person shouldn’t try using them. They can be incredibly effective. But they are what they are. Not a quick fix, and (to most people) not a long term solution.
Some doctor told my dad a while ago that he felt like we weren’t that far off from physically poking around in a mind and hoping that we fixed it- or that we’re closer to that than understanding it.
It’s an old and second hand story. I do appreciate the idea though that we’ve found ways to disrupt the mind that can be beneficial, but that we’re not at the level of being able to do more than throw a cog in the works in a general direction.
For me it makes it easier to accept when the first - or second thing does work. We’re just trying things. It’s not like we know what is gonna unclog the works.
This is getting pretty deep into a metaphor. Sorry
SSRIs are the most effective means we have in terms of medication. That doesn’t mean that they’re the solution. They’re a short term stop gap. The changing of routines and everything that goes on in appointments with psychologists is supposed to be the oil. Many times however that oil isn’t used.
Other than that we can only hope that we figure out some better tool for the job.
but having a proper solution would make selling meds for a long time harder!
weed has many medicinal effects, and yet it’s illegal in most places
LSD has many medicinal effects, and yet it’s not even allowed to be studied in most places! There’s so many stories out there saying how psychedelics outright cured someone’s depression or anxiety, but no proper in depth studies on them.
I think it’s because nobody is really looking for a cure, well, I bet a lot of doctors want to but sadly they depend on funding & legality of their research. The only way for them to do any studies is to get money from the money men & a permission from the goverment (also ruled by the money men), and since they’re trying to look into claims like “one dose of this cheap to make drug cured me of depression!” then the best business decision is to say “fuck off”
I enjoy exploring altered states of being and the first time I tried LSD, after maybe a week or so, I discovered I was suddenly capable of saying no to people. Before that I’d sacrifice my own wellbeing just so I could help another person with something minor. During the LSD trip I remember seeing myself in my mind and the other me told me “love yourself more”.
This is one account of hundrets, if not thousands, of ones similar to mine. LSD (and psychedelics in general) most certainly has properties that can be incredibly beneficial for mental health.
Per weed it helps you chill out lol, not much to say here, it’s alcohol lite but without being physically addictive. Wonderful for anxiety, just not long term most likely.
This is all awesome but any mind altering substance really needs to be used with a therapist when we are talking about average people in a large population. I’d also argue they both have benefits but their drawbacks are just too strong.
Weed is mostly non addictive but comes with other issues and isn’t perfect. Heart issues? Family history of schizophrenia? Either of those could be really bad. Is this a good argument for legalization and harm reduction? Yes. I’m not sure about widespread psychiatric use though. Perhaps more with a therapist but that therapist would be key - similar to the shamans of indigenous cultures.
I also totally agree with these not being long term. I love weed but the “420 smoke every dayyyyyyy” culture also ignores the need to work on yourself and do the work with a clear head. I think that internal (ideally drug free and sober) work gets you to the point of not only benefitting from these drugs but avoiding their abuse.
LSD is a double edged sword and I ackowledge that. Good trips can fix you, bad trips can break you. The thing I’m getting at is that there’s been little to no progress made in trying to understand that substance and its properties since it became illegal.
I’m not advocating for replacing therapy with LSD of course, just saying that there’s incredible potential in that substance that the world of science is being forced to ignore. And just as you mentioned - controlled use of psychedelics for the purpose of self growth has been a thing in many human cultures, the fact it’s being stigmatised so hard right now is just odd tbf
And yeah absolutely, I wholeheartedly subscribe to Watt’s quote “Once you get the message, hang up the phone”, there’s only so much your drugged mind can come up with, it can give you good starting off points but that’s only the beginning.
Oil doesn’t fix alignment of gears. Ideally, you need to precisely go in and realign the exact gear. But we don’t have that power. So we’re throwing rocks.
There’s other antidepressants that don’t do that. Mirtazapine for instance helps sleep, and has no real impact on sex. It’ll make you hungry, though. Buproprion will mess with your sleep but not sex, but you’ll have no appetite. They all have their own unique collection of side effects, well worth looking into other options if the ones from SSRI’s aren’t tolerable
Friendly reminder that sexual side effects of SSRIs are incredibly common, some medications effect more than one in four, but it is something that’s typically wildly underreported unless the practitioner brings it up, specifically, first. Not just “any side effects”.
There are multiple treatment options for people who encounter those side effects. They can range from poor libido/drive, to inability to obtain an erection or adequate vaginal moisture, to delayed or absent orgasm. All are common and all are frustrating. All can occur alone or with one or more partners.
If it’s impacting treatment or quality of life or your ability to stay compliant with meds, it’s absolutely worth discussing with your provider. There are other medications or alternative schedules to taking SSRIs. There are other meds that can be prescribed alongside SSRIs to accommodate for the side effects.
SSRIs definitely work for some people. It’s just that everyone’s brain chemistry is extremely different and complex. Doesn’t make it less scientific. Making the best guess is math and science.
I would say it even works for many people. We’re aware of the fact that it works, and we’re aware of the fact that it effects serotonin. We also know that serotonin isn’t what does the work. There’s something down the line that is affected by the processes of the body that just happens to react in the chain from the serotonin manipulation.
But all the other things that are affected in that chain can also do weird stuff to you if you’re unlucky. That’s why it’s important to have good communication with your physician during the process.
This is one thing where so many people I talk to got unlucky. For me, SSRIs were super lucky in that they helped alleviate depression caused by my anxiety which then helped me find other roots of the anxiety. Turns out undiagnosed ADHD is terrible for your anxiety - got diagnosed though!
Side effects for me have included stomach issues and weight not coming off even as my physical condition improves as I’ve started running again. I’ll take it for now until I start weaning off in the future. I wouldn’t say they were a lifesaver but they helped immensely.
I always recommend trying it if the doctor recommends it (and if you want it) even though I was unlucky and turned paranoid three pills in. I stopped taking them and it was over in a couple of days. So many people get helped by them and never say a word. People you and I wouldn’t ever assume were on them.
SSRIs were super lucky in that they helped alleviate depression caused by my anxiety which then helped me find other roots of the anxiety
You hit the nail on the head.
SSRIs are terrific at clearing some of the noise and making you more receptive to other therapy (namely talk therapy) and striking at the root of what’s causing the issue. I wouldn’t have even thought about talking to a therapist a year ago and it’s been revolutionary understanding my behaviors (especially those that I learned in childhood) and how I’m inadvertently passing them down to my kids.
Consequentially I’ve also been more aware of my wife’s behaviors and how she’s passing them down to the kids and she’s not quite as receptive to the criticism as I’ve been.
It really is eye opening to have a good long conversation about what’s troubling you with someone who understands the intricacies of how the mind works and how it pieces things together.
I totally understand that this is a necessary process for anti depressants but damn it sounds scary as fuck. “Eat these brain chemicals and come back and see us in a couple weeks”
“How does it work?”
“Fuck if I know it’s kind of like throwing a rock at an old machine. Just make sure you let me know if you experience any of the long extensive list of potential side effects!” Like damn im for sure not a doctor but that sounds like russian roulette with brain pellets to me. If Ecstasy (which was invented by a pharmacutical company to be medication) can permanantly fuck up your brain I would bet money that these pills certainly do the same. I bite my tongue anytime someone mentions they are considering it or talking to a doctor about it, their choice. But man it scares the fuck out of me. Ill just continue to sleep all the time and stay angry lol
Almost always a ticket, assuming that’s the only law you’re breaking. And they will certainly look for more!
Funny story, I was arrested in Chicagoland one time for not having a license. (Lost my wallet, still had to work.) Officer had a high school kid (cop wannabe) for a ride-along and wanted to demonstrate arrest and booking procedures.
In and out in 45 minutes but got stuck 30 miles from home.
“I would argue that masturbation is the human animal’s most important adaptation. The very cornerstone of our technological civilization. Our hands evolved to grip tools, all right—including our own. You see, thinkers, inventors, and scientists are usually geeks, and geeks have a harder time getting laid than anyone. Without the built-in sexual release valve provided by masturbation, it’s doubtful that early humans would have ever mastered the secrets of fire or discovered the wheel. And you can bet that Galileo, Newton, and Einstein never would have made their discoveries if they hadn’t first been able to clear their heads by slapping the salami (or “knocking a few protons off the old hydrogen atom”). The same goes for Marie Curie. Before she discovered radium, you can be certain she first discovered the little man in the canoe.” - Ernest Cline
Masturbation is an innovator. So many inventions go back to “because porn”. Take current AI development for example, there’s a massive drive because porn and porn has only one job.
Steve Goodman and John Prine are said to have written the “perfect” country song. Incorporating as it does trucks, trains, the rain, mama, drinkin’ and prison.
“Well, I was drunk the day my mama got out of prison And I went to pick her up in the rain But before I could get to the station in my pickup truck She got run over by a damned old train…”
Well it’s possible to retrofit, you need to be willing to open the wall which is not a bad thing as it allows you to make a frame so you can center the TV exactly where you want it.
While being over a fireplace causes the TV to sit too high, the real concern with that location is heat and particulate matter released from the fireplace.
If it works for you that’s great. Every one I’ve experienced is so high up that it is literally a pain in the neck.
I suspect a minority of TVs over fireplaces are rarely used, or just used for utility (news, etc). Those ones are usually the worst ones where you question the sanity of placing it there.
Also, after pondering it more, I also suspect really large TVs up higher with a father back seating position are less of an issue. If you visualize that, the angle of looking up gets shallower the farther back you go.
The cliche of TVs over fireplaces being bad starts with smaller tvs many years ago. I suspect your situation is a reasonable distance back. And your tv is big enough to support that distance.
I love when people are like “if you get a windfall of money you’ll probably go bankrupt. Look at the statistics from lottery winners, 70% of them end up broke.”
Ah yes, a subset of the population whose only common traits are that they gamble and make objectively terrible financial decisions. Obviously this group should be the benchmark for the financial literacy and money management of the general population.
True, though let’s not act as if the family and friends constantly asking for money or expectating it, old acquaintances suddenly claiming you abused/assaulted/scammed them knowing you’ll just settle out of court to get them to fuck off, haven’t happened even to fiscally responsible people as well.
There’s more than just bad financial literacy with some of them, as not all lottery winners are always broke gamblers. The majority are, but not all. So the fact that almost every single person loses it all in a couple years should indicate that it still has massive potential to make your life harder even if you know what you’re doing and don’t succumb to massive overspending.
I think I could actually lay low pretty easy. Everything I'd buy people know I've been saving up for for a while. And they all take time to get even if you have the money so it wouldn't be all at once.
Plus my "dream [property/vehicle/hobby items/etc]" are all fairly atainable. Like theres a certain classic vehicle I want that usually goes for 20-30k just the configuration I want is a little difficult to find.
Not all states allow you to collect winnings anonymously. I doubt your relatives are actively monitoring lottery winners, but there may be some sleazy, ambulance chasing lawyers that do and would “preemptively” reach out to family and friends to let them know they’re happy to represent them if they “just so happen” to suffer any damages from you.
Holy fuck get a better hobby than harassing random people on the internet. How about I block you instead, for being toxic and joining in on the dogpile?
Enjoy is a choice word, but you betrayed yourself when you said this “Ah yes Vine, definitely a relevant thing in 2023 that everyone references. Thanks for reminding me that Vine existed, I had actually forgotten.”
Everything you’ve received, you invited, and continue to do so.
But go ahead, keep us up there, popping into your thoughts when you think you’re happy, just to tell you this:
You missed a joke/reference, then got pissy. If this back and forth in this thread has caused you any turmoil, I’m sorry, but that’s completely on you mate.
It’s up to you to recognise that.
Take care bro, seems you have bigger problems than us.
You’re literally relishing in the idea of causing someone emotional or mental distress?
Maybe I am a clown, but you are a god damn sociopath if this is what you enjoy, take a step back and read what you just wrote, you ENJOY causing PAIN to others. You’re a sadist and the only thoughts I am carrying on this thread are “wow that guy is disturbing, his life must be terrible if he actually enjoys this”.
I hope you get the help and happiness that you most clearly need, because this sort of behaviour is troubling and points to some very significant problems on your end.
You replied to the wrong comment, and I reread what I put, nowhere did I say I enjoy causing pain to others, I’d advise you reread it…
Enjoy is a choice word, but you betrayed yourself when you said this “Ah yes Vine, definitely a relevant thing in 2023 that everyone references. Thanks for reminding me that Vine existed, I had actually forgotten.”
Everything you’ve received, you invited, and continue to do so.
But go ahead, keep us up there, popping into your thoughts when you think you’re happy, just to tell you this:
You missed a joke/reference, then got pissy. If this back and forth in this thread has caused you any turmoil, I’m sorry, but that’s completely on you mate.
It’s up to you to recognise that.
Take care bro, seems you have bigger problems than us.
Some Vines are so deeply embedded in my memory that I'm sure I'll still be able to quote them even after the dementia has destroyed my ability to recognize my loved ones.
In hospice, surrounded by grieving loved ones saying their last goodbyes, the nurse watching on as I'm drifting away confused and irritable, doing their best to ensure my passing is as comfortable as possible, with my last breath I'll mutter "road work ahead? Yeah I sure hope it does"...
Meanwhile most of the world never went on Vine, and its been gone for 6 years now.
Titling a post with basically “no homo” makes the majority of people go “huh why are they being casually homophobic” not “oh wow they are in a pool, so that’s like that one Vine from 6+ years ago!”.
But by all means join the lineup of people spamming vine quotes at me as if I knew or cared what they mean lol.
You can choose to ignore things you don’t understand on Lemmy. I don’t go into the Risa posts because I know they’re not for me. If something doesn’t make sense and you want to ask about it, go for it, but don’t get upset when the explanation isn’t one that makes sense to you. For a lot of people, popular Vines were everywhere for a while. Not everything on the internet is for you.
I was never at any point complaining, but sure you guys dogpile on me for not understanding your trash from the 2010s, sorry for not having an encyclopedic knowledge of every meme from the last decade lmao.
Y’all mofuckas need a better hobby than ganging on someone for not knowing some random reference.
lmao I made a flippant comment and then got dogpiled by 20 people screaming at me over it, literally everything I have said has been on the back foot as I am pummeled by people mocking me and being angry because I dared not to care about Vine and didn’t recognize some dumb homophobic sounding reference.
But no I am the one that cares so much, not the people spamming all my comments and sending me angry DM because I dared to besmirch the name of a dead website.
The person who should get a life and touch grass is you. You’re spending wayyy too much time replying to everyone, and whining about getting dog piled when you’re just agitating everyone else.
I was never on Vine, and I know what these things are because I’ve been on the Internet for the last few years. No offense, but this is an Internet place too.
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