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Scientists find humans age dramatically in two bursts – at 44, then 60

If you have noticed a sudden accumulation of wrinkles, aches and pains or a general sensation of having grown older almost overnight, there may be a scientific explanation. Research suggests that rather than being a slow and steady process, aging occurs in at least two accelerated bursts.

The study, which tracked thousands of different molecules in people aged 25 to 75, detected two major waves of age-related changes at around ages 44 and again at 60. The findings could explain why spikes in certain health issues including musculoskeletal problems and cardiovascular disease occur at certain ages.

“We’re not just changing gradually over time. There are some really dramatic changes,” said Prof Michael Snyder, a geneticist and director of the Center for Genomics and Personalized Medicine at Stanford University and senior author of the study.

“It turns out the mid-40s is a time of dramatic change, as is the early 60s – and that’s true no matter what class of molecules you look at.”

whome ,

47 tomorrow and I feel it

MonkderVierte ,

My dad had a depression at 60, got visibly older. Looks like him being over 60 is another factor.

dezmd ,
@dezmd@lemmy.world avatar
madcaesar ,

RIP

demizerone ,

Fucking great. I turn 44 next year.

TheGiantKorean ,
@TheGiantKorean@lemmy.world avatar

I def feel like I noticed this in my mid 40s. My face and hair all looked very different within a year.

Sam_Bass ,

Starting to believe it. Had a babyface for the first half of my life. Now i look like a retired state trooper

ChickenLadyLovesLife ,

44 is probably the average age at which people start paying for their kids’ college tuitions. That shit will age anybody.

DJDarren ,

I’m 44 next month.

Oh.

tiefling ,

TIL I turned 44 at 30

ripcord ,
@ripcord@lemmy.world avatar

Oh man, 30 was the best.

Sorry to hear yours isn’t.

Lexam ,

I turn 44 on Saturday! Yay!

PickleRick ,

😢. It’s the guardian though so take it with a huge grain of bs.

Landslide7648 ,

If only there was a way to look at the actual study, but oh no

xmunk ,

It was nice knowing you.

HWK_290 ,

44 and nevermore…

Sam_Bass ,

Yeah i swore up and down id be dead by 50. Over a decade past due and late fees are steep

RagingRobot ,

Obsolete

rustyricotta ,

Unless you have the blessed Asian gene where you’ll look 30 until your 70s. Several of my friends are far older than myself, but fit right in.

IamSparticles ,

My anecdotal confirmation is that I started having a lot more health issues in my mid 40s. My eyesight got a lot worse. I started having issues with high blood pressure and cholesterol. I’m about to turn 50 and things have mostly stabilized. Medication and more regular exercise helps. My eyes are still bad but they aren’t getting worse as fast as they were.

jordanlund ,
@jordanlund@lemmy.world avatar

1st heart attack at 49…

PalmTreeIsBestTree ,

Heart attack got my Dad at 48 ten years ago. If anyone has a preexisting heart condition like my father had, then you need to get checked up often or you might die sooner.

ChickenLadyLovesLife ,

I started playing Ultimate Frisbee again at 44 and quickly regained most of my youthful speed and jumping ability (and my tendency to huck). So for me it was like the opposite of this article’s contention. Age 52/53 was a lot worse as that’s when I started getting arthritis.

IamSparticles ,

Yeah, well, that’s why it’s anecdote and not data, right? Everyone is going to be a little different, but the trend is there 😆

ieatpwns ,

So is it kinda like extra stages of puberty?

ben_dover ,

i thought becoming 30 fucked me up enough already… so i have to go through this two more times, only it will be worse? ugh…

Senseless ,

I know what you mean. I make old people noises now, when I stand up from a low couch or sth.

girthero ,

Felt the same when i turned 30 years ago, but i improved my fitness from that point forward and improved things drastically for myself.

ChickenLadyLovesLife ,

I’m 57 and I bike 25 to 50 miles a day, four out of every five days. A lot of age-related problems can be forestalled just by exercising and not eating too much food - and it helps to not majorly injure yourself in the process. In my opinion, the primary problem with aging is that it gives you more time to become sedentary and overweight.

nilaus ,

Turned 44 6 months ago. Haven’t felt it yet. Guess it’s going to get rough soon…

GluWu ,

One morning you’ll wake up and every bone in your body will pop simultaneously. Then while you lay there aching you’ll let out a 6 mimutes and 20 second fart that doesn’t have a happy ending.

nilaus ,

The horror.

PrimeMinisterKeyes ,

Yeah West in his seminal “Scale” kind of corroborates the whole story.

https://lemmy.world/pictrs/image/28fb84b1-25c4-4c35-870e-9c3d7fdd34b4.png

It seems, though, that the molecular changes you are undergoing do not immediately translate into increased mortality, so you’re going to have several more years of - presumably - feeling well until the big drop-off starts for all of us at about 60.
BTW, because of its wide range of topics, its solid scientific underpinnings and its excellent intellectual accessibility, this is one of two books I positively think should be taught at any school, the other one being Solé’s “Phase Transitions.”

dezmd ,
@dezmd@lemmy.world avatar

Wait til you sleep wrong and wake up wondering how you threw your back our.

https://lemmy.world/pictrs/image/12f2f23b-f71f-4c41-9fa7-c49da47ffcf9.gif

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