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MaximilianKohler

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MaximilianKohler ,

There are already compostable alternatives to plastic bags being sold in stores like Target. I heard one of the issues is that people/companies refuse to pay more for them.

MaximilianKohler ,

Do you have a citation for that? That sounds like disinformation. Compostable bags are made from plants not plastic. www.makeitmatter.com/faq

New Class of Antibiotics Proves Potent Against Multi-Drug Resistant Bacteria (scitechdaily.com)

This study describes the identification of an antibiotic class acting via LpxH, involved in lipopolysaccharide synthesis having potent in vivo efficacy against bloodstream infections caused by the critical Gram-negative pathogens E. coli and Klebsiella pneumoniae. Further development of this class of antibiotics could make an...

MaximilianKohler OP ,

Be sure to actually read the blog. I made a post about this in another community and one person completely ignored the blog and used deceptive tobacco and oil industry tactics to spread FUD and disinformation. But people who actually read the blog should be immune to that.

For example, here is the reaction of a normal and knowledgeable person who actually read the blogs: twitter.com/chydorina/status/1767995009771647375

MaximilianKohler OP ,

Here’s an example of virtually no one out of 1.2 million people caring whatsoever: forum.humanmicrobiome.info/threads/…/post-760

This is the kind of thing that for me invalidates all those pro-natalism “large population = more chances that one person’s going to do something great” arguments. 8 billion people and a single disabled person is left to do it on their own. Especially when it’s something like this where anyone/everyone can do something to help, and 99.99999% of people just simply can’t be bothered.

MaximilianKohler OP ,

Dr. Alexander Khoruts (University of Minnesota GI, Director, UMN Microbiota Therapeutics Program) made a similar comment. …humanmicrobiome.info/…/designer-hit-panel-discus…

He asks an FDA adviser “Does the FDA care more about profits or people?”, and the response he gets is “one of the missions of the FDA is to protect the interests of commercial developers”. Another question to the advisor: “How much influence does the industry have over the FDA decisions?”, A: “A lot”.

MaximilianKohler OP ,

Yes, FMT is super experiemental. The point of the blog/website is not to convince people to buy poop, it’s to find ideal stool donors who may be able to cure a variety of diseases.

Maybe FMT is a good idea, but it’s still too unknown for me to accept it.

It can’t become “more known” unless a highly effective donor can be found. And such a donor can’t be found unless people start helping…

I don’t think FMT is appropriate to regulate as a supplement. The ingredients of supplements are known and standardized. FMT is an extremely complex and dynamic ecosystem. Yogurt is a handful of known microbes in a highly controlled environment. FMT vs yogurt is like the universe vs a zoo.

MaximilianKohler OP ,

I’d automatically assume it’s a scam, spam, or both.

Why?

The email linked to the blog. The question was asked at the end of the blog.

Even if a panacea type microbiome WAS discord, it won’t cure everything. Cancer is one immediate example.

You may be interested in humanmicrobiome.info/cancer/.

It already would be impossible for it to prevent many diseases. Viruses for example that enter through the sinuses, or again, cancers caused by viruses. Heck even then something like norovirus would still wreck you too.

This is not correct. Not everyone gets sick from x virus. The primary reason is differences in their immune system and gut microbiome. Some relevant links for you:

This sounds more like someone who knows some knowledge but isn’t an actual expert in it

No offense, but that describes your comment. The blog should absolutely not sound like that given that it provides citations for its claims.

Not to mention it’s a big ask to strangers who probably don’t even know what a microbiome is.

The 1.2 million people who were sent the email & blog are people who are already familiar with the humanmicrobes.org project. Many of them hold advanced medical & biology degrees.

I agree though that many people are still not familiar with the gut microbiome and FMT. Do you have any suggestion in this regard?

MaximilianKohler OP ,

y’all need some campaign and ad managers

As the blog notes, there is no funding for that.

I don’t see anything wrong with Zelle, and multiple payment options are offered.

I’d be glad to help how I can

That would be great! There are various discussions on the microbiome forum:

MaximilianKohler OP ,

There are at least as many spam/bot signups as there are humans, so account approval negates that completely. Forums aren’t time-based like lemmy and reddit, so there is no sense of urgency. Discussions can take place over months/years. It’s possible to turn on the ability to make a post prior to registering, then when your registration is finalized it gets posted, but I’m not sure how dependable that is. I wouldn’t want people losing content they tried to post due to some cache issue.

I haven’t bothered creating anything on Lemmy. I’ve been urging the Xenforo software developers to join the fediverse. Discourse forum software is doing it, so we may soon see discourse forums show up on lemmy.

MaximilianKohler OP ,

Speaking of, it also wouldn’t help anyone with an organ transplant either.

FMT may negate the need for most organ transplants. Eg:

Etc.

There is evidence that it would immensely help with preventing nearly all human-cell borne cancers however, and in my opinion, THAT’S something your messaging should focus strongly on.

Human Microbes doesn’t do any specific messaging/advertising. Just the website where it covers the gut microbiome regulating the entire body and playing a major role in virtually every aspect of health & development. I would think that narrowing the focus to one type of cancer for example would be detrimental.

you’re touting this as a cure all, when really it’s a mass preventative (which again, is still extremely important and something really big).

I think the potential for both prevention and treatment exists for most conditions that are currently beyond medical capabilities. And there is a ton of evidence for this in the wiki I shared. Sure, there are some things that FMT won’t be a solution to of course.

MaximilianKohler OP ,

I’m trying to make you realize that it you keep speaking of it as if it is, with only a single biased source, while not admitting the limitations, hurts such a cause greatly.

I think there may be a misunderstanding there. I certainly recognize that FMT and the gut microbiome have limitations.

There is statistically significant evidence that there’s a lot of potential here, but there is yet to be solid evidence that this actually treats most conditions.

That’s all I’ve said as well.

Anyway, you seem to think that FMT’s potential to treat/prevent most types of cancer is something that should be emphasized more. If you have specific suggestions I’m happy to hear them.

MaximilianKohler OP ,

I’m doubtful that creating a lemmy community would funnel people to the forum. There is a lot to like about the forum format over time-based ones like lemmy. And the lemmy software is much newer and more incomplete/deficient than Xenforo. I think creating a lemmy community might just lead to fracturing of content/discussions, which would be detrimental. Also, unless you host your own instance it’s not super reliable (as we’ve seen with reddit and other reddit-alternatives).

MaximilianKohler OP ,

There’s a reason sites like Reddit sprang up and grew huge despite forums having already existed.

Yeah, but it comes with many major downsides that have become more apparent in recent years. For example, even lemmy seems to get hit hard by astroturfing, misinformation, disinformation, and toxicity. That’s more rare and easier to prevent on forums I think.

It’ll expose more people to the topic though.

Yeah, I was considering using lemmy instead of creating a forum, but decided on the latter after weighing the pros and cons.

MaximilianKohler OP ,

There have been efforts to change the “fecal” part of the wording, but it’s largely been unsuccessful. I personally don’t think it’s the biggest problem to focus on. I’d rather try to educate people that healthy poop is not repugnant. They think it’s gross because their own poop is unhealthy.

MaximilianKohler OP ,

Not sure if this was it, but I tried again a day later and I didn’t select “english”, I left it as undefined, and it worked.

MaximilianKohler ,

Not open-source, but I was using Metacritic as an alternative to Steam. Unfortunately, they’ve severely degraded their UI in recent years so I started using GOG.

MaximilianKohler ,

Doesn’t that mean that docker containers use up much more resources since you’re installing numerous instances & versions of each program like PHP?

MaximilianKohler ,

Doesn’t that mean that docker containers use up much more resources since you’re installing numerous instances & versions of each program like mumble and leftpad?

MaximilianKohler OP ,

Since you posted this into a self-hosting community…

I have two other websites hosted on a $5 Hetzner server (that counts as self-hosted right?). I’ve been considering adding a Wordpress, Grav, or static site to it. But as mentioned in the OP, I have to worry about the site going down if it gets a traffic surge, so I’m thinking it would be safer and similarly/more affordable to host a Wordpress site with Hostinger or GreenGeeks. Am I wrong?

Grab a Raspberry Pi, slap nginx proxy manager and ddclient into it, and point your domain to your home IP.

I’m not likely to do that, for multiple reasons.

MaximilianKohler OP ,

I’d recommend Statamic

I looked at the demo and it looks like a very simple text editor to make blogs.

MaximilianKohler OP ,

Why are you worried about your site going down during traffic surge? Unless you’re running a critical service, there is no need to worry about this too much if it’s just your personal sites.

Because it’s an important business website that would have severe consequences if it went down during traffic spikes (which it does get).

With proper caching, your personal site can even tank traffics from reddit frontpage on a $5/mo vps.

Yeah, I’m using Cloudflare, and I saw that Wordpress has a built-in caching option, but I couldn’t find any info on how well that protects sites from traffic surges.

consider hosting it on platforms with autoscaling support such as netlify.

Yeah but I need an SSG with the same capabilities as Squarespace to do that, and as mentioned in the OP, that doesn’t seem to exist.

MaximilianKohler OP ,

Redline the cheapest option until it catches fire.

It’s an important business website that would have severe consequences if it went down during traffic spikes (which it does get).

MaximilianKohler OP ,

I covered that in the links in the OP. It’s extremely limited. I didn’t find it useful.

MaximilianKohler OP ,

Thanks!

MaximilianKohler OP ,

I covered that in the OP. It requires coding ability for anything other than a simple blog.

MaximilianKohler ,

Fedora, Ubuntu, Debian, or PopOS

What about Arch? I was told:

mint is garbage. The only thing easier about mint or any of those “noob friendly” distros is the initial install

any time you want to do anything outside of its strict little ecosystem it becomes a massive headache

arch’s wiki is unparalleled

MaximilianKohler ,

What about Arch? I was told:

mint is garbage. The only thing easier about mint or any of those “noob friendly” distros is the initial install

any time you want to do anything outside of its strict little ecosystem it becomes a massive headache

arch’s wiki is unparalleled

MaximilianKohler OP , (edited )

Lemmy has pretty much all the same problems as reddit does but at a much smaller scale because it’s just not as big. Would you suggest Google use Lemmy?

I agree, and I covered that in my blog. Lemmy is astroturfed and may even be easier to astroturf than reddit. I would like to see a more diversified “discussions and forums”, that’s not just reddit links.

In general, privately-owned forums (running Xenforo, etc.) seem much better run than most reddit subs. I have never experienced the plethora of problems with reddit, on forums. I think it’s harder to spam and astroturf forums, and the owners & moderators have different incentives than reddit mods.

The bar to entry as a new person on smaller forums was often high.

I don’t remember experiencing that, but it makes me think of the bar to entry for running a reddit sub. Anyone can instantly create one for free and do whatever they want with it and get on the top of search results pretty quickly. Setting up your own forum is a lot more difficult and more of a commitment. I think there are benefits to that.

I agree with your last paragraph. I think the type of warnings Twitter implemented are a decent idea. I think in general people need more warnings that what they see on reddit and other social media is not policed for legal content – people can and do say whatever they like, and much of what people say is misinformation and disinformation.

I don’t think most people realize that reddit and other social media platforms have no obligation to take down illegal content. People seem WAY too trusting of things they read on reddit. If Google is going to be highlighting reddit results and putting them at the top, then they bear some responsibility for this.

Since the CDA’s passage in 1996, § 230© has been consistently interpreted by U.S. courts to provide broad immunity to platforms for hosting and facilitating a wide range of illegal content—from defamatory speech to hate speech to terrorist and extremist content.12 Notice of illegal content is irrelevant to such immunity.13 Thus, even if a platform like YouTube is repeatedly and clearly notified that it is hosting harmful content (such as ISIS propaganda videos), the platform remains immune from liability for hosting such harmful content.

MaximilianKohler OP ,

Yes, I understood that. I never experienced it.

MaximilianKohler ,

I don’t really don’t understand the dislike of Reddit

Have you been living in a cave? github.com/MaximilianKohler/Archive/wiki/Reddit

MaximilianKohler ,

Yeah, here’s a fantastic recent article about it:

The Discussion Forums Dominating 10,000 Product Review Search Results - Reddit’s dominance and the downsides of that detailed.com/forum-serps/

MaximilianKohler ,

if I wanted to bring the Fediverse down or at least keep my customers from going there, I would sow this stuff as much as I can

Agree. And that’s been my experience here too. I made two posts critical of reddit and they each seemed to have been astroturfed by toxic reddit shills.

I think it would require a lot of active and dedicated mods and admins, which I’m doubtful is doable. I don’t know that there’s a fix for this but a “true block” (instead of the current “mute”) might help; but there are major downsides to that type of feature as well. I wrote in a blog that it might require an advanced AI to moderate everything.

MaximilianKohler ,

And to the contrary, I’ve seen people claiming blatant bad-faith behavior as “just disagreement”.

MaximilianKohler ,

Here. Strangely, on Reddit I get much more support. Lemmy is either filled with trolls or is being astroturfed by people who don’t want to see it thrive.

I have never ever ever seen proof that Lemmy is pro-Reddit at anything.

Here’s the latest time it happened: lemmy.world/post/11328086

The previous one was deleted, which unfortunately covered it up.

YSK: Do You Really Need That Antibiotic? It’s antibiotic season. Brush up on how you should use them — and when to avoid them. (NYT, Dec 2023) (www.nytimes.com)

It’s refreshing to see a major news outlet discussing collateral damage and not just resistance. Over the past decade, 99% of the time antibiotic overuse is covered and warned about it’s always only in regards to resistance....

MaximilianKohler OP ,

Fiber won’t re-add the microbes that antibiotics killed off. Neither will probiotic supplements, but some of them are proven to be beneficial. humanmicrobiome.info/probiotic-guide

MaximilianKohler OP ,

Can you tell me why you are confidently spreading harmful disinformation? Do you enjoy people being harmed?

humanmicrobiome.info/antibiotics/

MaximilianKohler OP ,

That’s not “some blog”, so what I can gather is that you’re either extremely unintelligent or you’re purposely trying to harm people.

Should I move to Docker?

I’m a retired Unix admin. It was my job from the early '90s until the mid '10s. I’ve kept somewhat current ever since by running various machines at home. So far I’ve managed to avoid using Docker at home even though I have a decent understanding of how it works - I stopped being a sysadmin in the mid '10s, I still worked...

MaximilianKohler ,

It seems like docker would be heavy on resources since it installs & runs everything (mysql, nginx, etc.) numerous times (once for each container), instead of once globally. Is that wrong?

MaximilianKohler ,

Instead of setting up one nginx for multiple sites you run one nginx per site and have the settings for that as part of the site repository.

Doesn’t that require a lot of resources since you’re running (mysql, nginx, etc.) numerous times (once for each container), instead of once globally?

Or, per your comment below:

Since the base image is static, and config is per container, one image can be used to run multiple containers. So if you have a postgres image, you can run many containers on that image. And specify different config for each instance.

You’d only have two instances of postgres, for example, one for all docker containers and one global/server-wide? Still, that doubles the resources used no?

MaximilianKohler ,

It seems like docker would be heavy on resources since it installs & runs everything (mysql, nginx, etc.) numerous times (once for each container), instead of once globally. Is that wrong?

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