In the beginning when you explore one of the starting areas you can encounter a prostitute who offers herself for cheap. If you agree, she tells you to follow her into some backroom. However, there is a giant dude waiting inside who knocks you unconscious and takes all your money (it’s scripted, you can’t escape this fate once you enter the backroom).
FC5 also has the option to finish the game in a couple of minutes if you do what the antagonist asks. Don’t remember what exactly it was, leave with your team, I believe.