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kbin.life

Secure Boot, signed kernel modules (for shitvidia), and the Shim - Why does the kernel need to support SB after the handover? Can a graphics coprocessor just run as a hotpluged module unsigned?

Asking about why the kernel needs to support secure boot on an individual system where I am not concerned about the hole punched by the nvidia kernel module. I’m concerned about the proprietary boot loader firmware that will never be maintained well. I’m not asking if it is a good idea in general or for most people....

pathhunter β arrestin assay

β-Arrestin recruitment is a ubiquitous mechanism of negative regulation of GPCR signaling, which has been demonstrated for almost all GPCRs. Recently, β-arrestins have been shown to act as signaling scaffolds for numerous pathways, such as Akt, c-Src, and ERK 1/2, in a G protein-independent manner. G protein and β-arrestin...

Is NextCloud worth it for a company?

I selfhosted my Nextcloud and really enjoyed it for personal use. One of my friends took a look into it and thought that it could be a good thing for his company that employees +200 people and growing… They are currently using Google Workspace but want to ditch it completely in favor of something that they can control...

histology stains list

Histological staining plays a critical role in the visualization of tissue and cell structures. Living cells or fixed cells have very few inherent colors and only very small differences in the refractive indices of their component parts. By staining tissue sections, pathologists and researchers can view tissue morphology...

cfse staining

Amine-reactive dye CFSE (carboxyfluorescein diacetate, succinimidyl ester, also known as CFDA-SE) is widely used in cell proliferation and in vivo cell tracking. CFSE is non-fluorescent until it enters viable cells, where it is hydrolyzed by cytoplasmic esterase enzymes to release fluorescent amine-reactive dyes. These dyes then...

My 7 year old loves to tell people "bite my shiny metal ass" and it's awesome.

Wife and I decided to do another watch through before the new episodes. The 7 year old caught a couple and now he’s hooked. His favorites to quote are Bender and Zoidberg. It’s especially cute when he goes “wub wub wub!” At the grocery store. I’m so proud.

What are the best instruments for a beginner to pick up?

So i have (i think) no mucical talent becasue in school i was always bad at music classes and was behind compared to others also i coudent stand all the noises going on. im not sure why but i wanted a keyboard pinao becasue i like the way they sound, once i got one i tried to have some folks teach me but i imeditly got...

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