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OopsAllTwix ,

Silver or gold spray paint in a sock is good for staying frosty.

KillingTimeItself ,

if you think drug euphorias are high.

Just wait until you find out what the lows are like.

2ugly2live ,
@2ugly2live@lemmy.world avatar

Man, I’ve been tempted. I’ve started saying I’d try a drug if it was ever offered, because I’m too much of a coward to figure out how to get it myself. I have an additive personality, so I know it would kill me and, honestly, I’m fine with that.

Semi_Hemi_Demigod , (edited )
@Semi_Hemi_Demigod@lemmy.world avatar

One must be always drunk, that’s all that matters.

But what with?

With wine, with poetry, or with virtue, as you choose.

But get drunk.

whoisearth ,
@whoisearth@lemmy.ca avatar

Amen. Virtue is the bomb, but also rum

tootnbuns ,

Word

kandoh ,

Green Maeng Dae and THC gummies are all that keeps me going some days

Dozzi92 ,
@Dozzi92@lemmy.world avatar

Kratom cut my drinking by 80%. Haven’t had a single beer at home alone in years. Still go out occasionally with friends, so not a recluse or anything, just the excess stuff.

Shyfer ,

Sounds expensive lol

cows_are_underrated OP ,

Depends on the drug.

beejboytyson ,

I was talking about how hard it was for me to cut 5 pounds for my fight. This one guy told me I should take up meth to make weight. Genuinely look at him with utter confusion.

Snowclone ,

Had a lady demand I hire more meth addicted as ‘‘they work really hard for nothing’’

I declined her business advice.

kandoh ,

He’s right. They used to put meth in chocolate and marketed it as a great way for housewives to lose weight while keeping their home tidy.

Reucnalts ,

Didnt know about housewifechocolate i only knew Panzerschokolade, but it wasnt for the wifes at home. But i mean who doesnt need a wife at home who is working at home and still has the energy to work you

Dasus ,

Alcohol is a depressant my man.

Neurologically speaking, so in a different context, yeah, but neurological depression also seems to lead to actual depression, the mood disorder, which also show up as neurological depression.

We really need better imaging tools to measure neurotransmitter activity, would make for several advancements I’d say

GiveMemes ,

Abuse of any psychoactive drug on the regular leads to depression. It isn’t just this concept of depressant or stimulant or even related in any way. Any stimhead can tell you all about the suicidal ideation inducing comedowns and inability to get anything done after stopping use.

Dasus ,

Abuse of any psychoactive drug on the regular leads to depression.

That’s a biased generalisation.

While abusers of psychedelics are rare, they’re generally manic and psychotic moreso than depressed.

Yes, depression can be caused by any addiction and abusing stims can cause a lack of neurotransmitter due to exhausting the resources for the body to do so.

It’s a bit different than using something that’s a direct depressant though.

GiveMemes ,

Depressant isn’t linked to depression tho. Get that idea out of your head completely. Like seriously go read some neuro textbooks and stop getting your pharmacology info from tiktok. Depressants depress the CNS… depression is a mental illness.

Also I’ve abused psychs and known a few others that did and I wouldn’t call any of our our activities/side effects manic or psychotic by any means. I know one person who had a family history of schizophrenia that had negative effects like that from their abuse. But just the one. I’d be interested in scholarly articles about the subject tho since I have biased data, and apparently, yours is not, at least from what one would construe from your comment.

Dasus ,

Isn’t linked?

That’s just wrong. Correlation is a link. The long term high dose use of any CNS depressant correlates with actual depression (the psychological issue [I added the brackets because you seemed to miss when I specified the difference earlier.])

Oh wow, an anecdotal story, well that just proves what you’re saying is 100% correct.

Science couldn’t possibly disagree

“Pure” psychedelics like LSD and psilocybin rarely cause any sort of abuse, really, but I’ve been on a drug abuse closed ward and the manic people were generally in there because of CNS stimulants of all sorts. Psychedelics are just less likely to yield any long-lasting harmful effects compared to say smoking crack or snorting meth.

So yeah, while a CNS depressant isn’t the a thing that directly causes psychological depression as such, you can probably see how they’re linked from the following analogy; imagine that I tie your legs together. That doesn’t remove your ability to walk, per se, as long as you remove the restraints. But if no-one removes them for 50 years, do you think you’d walk as well as before?

In much the same way, yes, CNS depressants are linked to depression, and alcohol and benzos are the clearest examples.

www.ncbi.nlm.nih.gov/pmc/articles/PMC8238014/#:~:….

americanaddictioncenters.org/…/depression#:~:text….

GiveMemes ,

This one is a CNS stimulant.

verywellmind.com/adderall-for-depression-4845418

So is this

www.frontiersin.org/journals/…/full

They’re both linked to depression too. My point is that you need to get this idea of correlating the terms because of how they look similar out of your head. It’s a result of drug abuse (addiction/overuse) and the consistent changes caused by that in brain chemistry, causing negative effects when they aren’t affecting you. It’s not a result of it being a depressant vs a stimulant that you’re addicted to. A depressant, when not abused, relieves symptons of depression (and even when abused, often relieves them upon intake). Not going to get into how stimulant mania is likely caused mostly by lack of sleep, but you can look into it if interested.

And you’re right that psychedelic abuse hasn’t been linked to increased depression or anxiety… mostly because there’s no research on it whatsoever. In fact, almost all of our studies on drug abuse and addictiveness are incredibly flawed in the first place. That doesn’t make your anecdotal experience from a drug ward any more powerful tho, especially as it’s going to self select for people with mania as they are more likely to both be committed by the state and by their family or friends, more likely to cause people to take notice and sit them down, etc.

Analogies are great when it’s not medicine. Medicine is really fucking complicated tho. We can have a veritable chemical pathway and successful trials in animal testing and still end up with a result we shouldn’t expect.

My point is not that CNS depressants don’t cause depression from abuse, but that it’s just a result of abusing drugs, not the fact that they’re a depressant class drug.

Dasus ,

Yes, abusing drugs of other classes can cause depression too.

Who ever argued it didn’t?

A depressant, when not abused, relieves symptons of depression (and even when abused, often relieves them upon intake).

It also relieves those symptoms despite being abused.

on drug abuse and addictiveness are incredibly flawed in the first place. That doesn’t make your anecdotal experience from a drug ward

I literally emphasised how anecdotal experiences aren’t evidence enough, which is WHY I LINKED ACTUAL PEER REVIEWED DATA.

My point is not that CNS depressants don’t cause depression from abuse, but that it’s just a result of abusing drugs, not the fact that they’re a depressant class drug.

And you’re wrong. First off, research the difference between the terms “addiction” and “dependence”, and then read the science I just linked in my previous reply.

You’re willfully ignorant, pretending you understand a subject you’re barely conversant in. (Why do people feel the need to do this online?)

I used the analogy, because it’s literally how the depression causing part of downers caused psychological depression; by long-term CNS depression.

That’s why alcoholism is so strongly linked to depression. Just like benzo abuse and opioid abuse, but unlike meth, speed and other stims, which tend to cause mania.

(I feel like I’m repeating myself here. Probably because I am, and you just keep ignoring the actual science, because it proves you wrong and you’re not man enough to admit to having not understood something perfectly.)

www.ncbi.nlm.nih.gov/pmc/articles/PMC8238014/#:~:….

americanaddictioncenters.org/…/depression#:~:text….

www.ncbi.nlm.nih.gov/pmc/articles/PMC9834328/

ajp.psychiatryonline.org/doi/…/ajp.138.11.1508?do…

ajp.psychiatryonline.org/…/ajp.2006.163.7.1149

lath ,

Randomly read a click bait article the other day on “How famous people died”. The older ones were alcohol + drug prescription overdose, while the newer ones were fentanyl + cocaine + alcohol.

Remember people, stay hydrated! Drink your drugs with water like you’re meant to!

Etterra ,

NGL, if she showed up to help me I’d demand to know who funded all that shit and why they couldn’t have spent that money on actual public healthcare.

Blackmist ,

Now nothing is fun and nobody trusts to not to steal anything that isn’t nailed down.

hanrahan ,
@hanrahan@slrpnk.net avatar

Alcohol is a depressant ?

Maggoty ,

Crucially, it doesn’t seem like one while you’re high on it. For most people anyways.

cheddar ,
@cheddar@programming.dev avatar

I’ve heard that drugs, including alcohol, trigger the chemicals in our brains that make us feel “happy”. After the effects wear off, our natural “happiness” level is even lower than it was before. This is why we feel the need to use the drug again, and over time, we also have to take more of it to feel the same level of “happiness”.

Dozzi92 ,
@Dozzi92@lemmy.world avatar

Doesn’t “depressant” have more to do with your body’s functions and not necessarily the depression we think about? Been a long time since high school health and EMT classes.

arefx ,

Yes, but if you become an alcoholic you will be depressed and feel like a piece of shit regardless.

8.5 years sober, thank fucking god.

cley_faye ,

Because some people think that getting high as a kite is a suitable way to not be depressed.

Triasha ,

Anhedonia is horrifying if you think about it.

captainlezbian ,

It’s horrifying if you feel it too

Triasha ,

If you do I’m sorry.

captainlezbian ,

I don’t always, but I sometimes do. I used to a lot though. Didn’t really feel much of anything but a dull ache as a teenager. Thank fuck I’m past that

Triasha ,

I’m glad it’s better.

OhStopYellingAtMe ,
@OhStopYellingAtMe@lemmy.world avatar

My dearest friend for the past 25 years became a drug addict. She died of an OD on Saturday. Left two young children with no parents. (Dad left years ago). I witnessed her spiral into addiction and destruction over the past 2 years. I couldn’t stop it. I tried.

If you want to become an addicted to something, please try masturbation or video games.

tacofox ,

I’m sorry about your loss ❤️

boatsnhos931 ,

Way to kill the vibe

jdeath ,

this fucking guy

boatsnhos931 ,

My bad I forgot this was a serious community. I’ve got to cut down on the heroin and whiskey

OhStopYellingAtMe ,
@OhStopYellingAtMe@lemmy.world avatar

Sorry. :-(

boatsnhos931 ,

It’s ok, when I go to a show I always talk about everyone I know who has died while driving drunk and how good of a person they were

BonesOfTheMoon ,

I’m sorry for your loss. Addiction is terrible.

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