GPU support is a real mess. Those ARM SOCs are intended for embeded systems, not PCs. None of the manufacturers want to release an open source driver and the blobs typically don’t work with a recent kernel.
For ARM on the desktop, I would want an ATX motherboard with a socketed 3+ GHz CPU with 8-16 cores, socketed RAM and a PCIe slot for a desktop GPU.
Almost all Linux software will run natively on ARM if you have a working GPU. Getting windows games to run on ARM with decent performance would probably be difficult. It would probably need a CPU that’s been optimized for emulating x86 like what Apple did with theirs.