I would argue that next step YouTube is going to pull is just in time video mixing where they will overlay add on top of your video. This would make adblockers unable to block since it’s indistinguishable from regular video. However efforts like SponsorBlock would become dominant way of blocking ads. At which point YouTube will probably resort to preventing skipping video while ads are playing.
At not poing will it occur to them all of that is a waste of time and that there are smarter ways to earn money without gouging people’s eyes out. At the moment this is not happening because it’s too CPU intensive.