Unfortunately I think there’s been a good bit of evidence recently that people WILL accept it. As a prime example lemmy hasn’t exactly replaced reddit despite the relative uproar that the API changes caused. Netflix & co just keep hiking prices and people just keep buying it.
And then on the technical side, if the ads are coming from the server it’s possible youtube might just refuse to serve the rest of the video stream until all or most the ad’s runtime has passed. It depends on how serious they want to get about capturing the revenue lost to adblock users.