Study reveals metabolic switch crucial for memory T cell formation and cancer immunity
Led by Ludwig Lausanne’s Ping-Chih Ho and Alessio Bevilacqua and published in the current issue of Science Immunology, the study identifies PPARβ/δ, a master regulator of gene expression, as that essential molecular switch. Ho, Bevilacqua and their colleagues also show that the switch’s dysfunction compromises T cell...
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