The research, published in the journal Molecular Cell, explores members of a family of proteins called serpins, which are implicated in a number of diseases. The research is the first to investigate how the location and composition of carbohydrates attached to the serpins ensure that they fold correctly. Serious...
Insulin is a hormone that decreases blood glucose levels. The only cells that produce insulin are pancreatic beta cells (β-cells), and a decrease in these cells is a major cause of diabetes. Although therapies aimed at increasing pancreatic β-cells are eagerly awaited, a strategy that can increase β-cells has, thus far, not...
Spain’s much-maligned system for evaluating scientists, in which the sole criterion for career advancement is the publication of papers, is set to be overhauled under new proposals from the country’s National Evaluation and Accreditation Agency (ANECA)....
Scientists have detected the most powerful cosmic ray seen in more than three decades. But the exact origin of this turbocharged particle from outer space remains a mystery, with some suggesting that it could have been generated by unknown physics....