Yes, you can check if models have certain sizes or cover certain areas. However making this code robust will be difficult. Probably the most robust option is having a “base” minimal model like a black rectangle that is always loaded. Then you can apply custom models (or the default models) on top.
However you can’t stop users from cheating in general. It is their device and ultimately they can hack around any checks that you add. Other than oppressive DRM/anti-cheat/remote attestation you can’t ensure that the run exactly the code that you want them to run.