The Libertarian Party had a female VP nominee in 1972. Later, Jo Jorgensen was the VP nominee in 1996 and then the Presidential nominee in 2020. I can only imagine that the LP’s voters are pretty far down the transexuality path by now.
EDIT: And that’s just the US. I can but imagine the situation in other countries. Think of the UK, what with all those Conservative voters for Margaret Thatcher and Theresa May.