Yes - they’ve been attacking her pretty much from day one, but that was just to feed the base - to keep them on a steady diet of hatred.
It’s different now, and at this point, pretty much the dumbest thing the GOP could possibly do would be to try to attack Harris personally. It would appeal to the base, but they don’t need to appeal to the base, since the base is voting Trump no matter what. They need to appeal to the moderates and independents, and I don’t see any way personal attacks are going to do that. If they try it from a moral or legalistic stance, Harris clearly has the high ground, and will mop the floor with them. And if they try to do it in a personal level, it’s guaranteed that somebody, and likely the wannabe dictator himself, will say something overtly racist and/or sexist, and that will pretty much immediately hand Harris the victory right there.