Some groups of people will be hurt, and other groups will be helped. The groups that will be helped are the ones that vote and pay taxes, and even in liberal areas these groups are running out of patience with being on the giving end of expensive but apparently ineffective local programs to deal with homelessness the nice way.
“I don’t care where you go but you can’t stay here” doesn’t work if it’s the policy everywhere, but the alternative appears to be a situation where cities that do more to help the homeless simply attract homeless people from other places until they too are overwhelmed. (It’s a big issue in NYC with the large numbers of migrants arriving here, but the city is required to provide them with shelter by the state constitution so the Supreme Court ruling won’t have a direct effect.)
I think local and state level solutions are fundamentally unsuited to actually solving the problem but I don’t expect a federal solution either, especially if Trump is elected. So it seems like LA, San Francisco, and other places with an insurmountable liberal majority and good weather all year are simply screwed.