I love mushrooms and I have PTSD. It’s helpful. But, MDMA deconditions the fear response in most people far more effectively.
I’ve seen this first hand again and again and again. I grew up in the rave scene. Still in the burner scene. Still in the psychedelic scene.
MDMA promotes a sense of safety that’s integral to treating PTSD. Your link is to a class summary? It doesn’t support the numbers you just cited, as far as I could see. Unless you’re referring to that one linked animal model study.
Here’s a review of both. While psilocybin is of interest in treating PTSD, studies so far have been minimal.
As I said, MDMA is the gold standard for treating PTSD. That’s why MAPS has invested so heavily into it.
Psilocybin is excellent for treating other things. End of life anxiety and depression, for example. John’s Hopkins has invested a lot in research here.
I know the landscape. So, do the therapists and researchers who are studying and investing their time into it. MAPS put their money on MDMA for PTSD because they’ve seen it work better than other psychedelics. Rick Doblin is the protégé of Stanislov Grof, who was a leading LSD researcher before it was criminalized. These aren’t shots in the dark or even educated guesses. But a painstaking effort to prove to the Feds that these drugs (both of them) need to be usable legally in psychiatry.