If it’s a closed binary-only game then I really don’t care what “runtime” it uses as long as it runs well. Almost all games use their own GUI so they won’t be integrating with anything anyway and since they are closed I won’t be able to build them from source. It either runs and plays well or it doesn’t. Using Wine as the runtime is not that different from a game like Slay the Spire running in a JVM.
So I have no problem with switching stuff over to Wine/Proton if that works better.