I’m not familiar with Nobara, but I can at least show how I would install pyUSB for use in Debian:
If you follow the instructions exactly as in the readme, it will error:
<span style="color:#323232;">$ pip install pyusb
</span><span style="color:#323232;">error: externally-managed-environment
</span><span style="color:#323232;">
</span><span style="color:#323232;">× This environment is externally managed
</span><span style="color:#323232;">╰─</span><span style="font-weight:bold;color:#a71d5d;">></span><span style="color:#323232;"> To install Python packages system-wide, try apt install
</span><span style="color:#323232;"> python3-xyz, where xyz is the package you are trying to
</span><span style="color:#323232;"> install.
</span><span style="color:#323232;">
</span><span style="color:#323232;"> If you wish to install a non-Debian-packaged Python package,
</span><span style="color:#323232;"> create a virtual environment using python3 -m venv path/to/venv.
</span><span style="color:#323232;"> Then use path/to/venv/bin/python and path/to/venv/bin/pip. Make
</span><span style="color:#323232;"> sure you have python3-full installed.
</span><span style="color:#323232;">
</span><span style="color:#323232;"> If you wish to install a non-Debian packaged Python application,
</span><span style="color:#323232;"> it may be easiest to use pipx install xyz, which will manage a
</span><span style="color:#323232;"> virtual environment for you. Make sure you have pipx installed.
</span><span style="color:#323232;">
</span><span style="color:#323232;"> See /usr/share/doc/python3.11/README.venv for more information.
</span><span style="color:#323232;">
</span><span style="color:#323232;">note: If you believe this is a mistake, please contact your Python installation or OS distribution provider. You can override this, at the risk of breaking your Python installation or OS, by passing --break-system-packages.
</span><span style="color:#323232;">hint: See PEP 668 for the detailed specification.
</span>
Instead, I would create a virtual environment (I’m using virtualenv instead of venv)