I assume you’re talking about Desktop Environments. Yes, of course. KDE and Gnome rival MacOS as far as usability goes. The better part is that other software development groups port their software over to Linux as well and make it as seamless as possible.
People run into confusion here when people flood the comments on user questions like this, so let me shut that down right now.
If you need something that is a straight Desktop Environment, get a distro with KDE or Gnome, and a known OS that will have a lot of user base getting questions and answers if you even run into any.
Fedora or Ubuntu. Don’t listen to anyone arguing for their preferred favorites.
Don’t listen to performance comments.
You want a solid, no issues, not needing to look for help kind of distro. It’s those two, no question, and they both have KDE and Gnome variants.