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Study reveals metabolic switch crucial for memory T cell formation and cancer immunity (www.news-medical.net)

Led by Ludwig Lausanne’s Ping-Chih Ho and Alessio Bevilacqua and published in the current issue of Science Immunology, the study identifies PPARβ/δ, a master regulator of gene expression, as that essential molecular switch. Ho, Bevilacqua and their colleagues also show that the switch’s dysfunction compromises T cell...

Peloton to ruin the secondhand market by charging a $95 ‘used equipment activation fee’ | It doesn’t apply to refurbished models bought directly from the company (www.engadget.com)

Peloton is in something of a financial rut lately, and we all know what companies do when that happens. They take it out on consumers. To that end, the exercise machine maker just announced it will be charging a $95 “used equipment activation fee” to anyone who buys one of its machines on the secondhand market, according to...

Israeli society’s dehumanization of Palestinians is now absolute (www.972mag.com)

At 5:40 a.m. on Aug. 10, the IDF Spokesperson sent a message to reporters informing them of an Israeli airstrike on a “military headquarters located in Al-Taba’een school compound near a mosque in the Daraj [and] Tuffah area, which serves as a shelter for residents of Gaza City.”...

Snow Bros. Wonderland Gets Worldwide Release This November | Time Extension (www.timeextension.com)

Snow Bros. Wonderland, a sequel to the beloved arcade game Snow Bros., is scheduled for worldwide release on November 28th, 2024 by Clear River Games and Tatsujin. The eagerly anticipated title will be available on PS5, and Nintendo Switch both physically and digitally. The PS4 release will be digital only....

Welche Klimaschutz-Maßnahmen helfen wirklich? (www.scinexx.de)

Auf dem Prüfstand: Tausende Klimaschutzmaßnahmen wurden bisher in verschiedenen Ländern umgesetzt – aber nur 63 dieser Maßnahmen trugen in größerem Umfang zur Reduktion der globalen Treibhausgas-Emissionen bei, wie eine Auswertung ergab. Der Erfolg dieser Klimapolitik beruht meist auf einer Kombination von...

Microsoft will try the data-scraping Windows Recall feature again in October | Initial Recall preview was lambasted for obvious privacy and security failures (arstechnica.com)

Microsoft will begin sending a revised version of its controversial Recall feature to Windows Insider PCs beginning in October, according to an update published today to the company’s original blog post about the Recall controversy. The company didn’t elaborate further on specific changes it’s making to Recall beyond what...

New Computational Model Matches Drugs to Protein Synthesis Disruptors in Hereditary Diseases, Cancer (www.genengnews.com)

Details of the model, which is called RTDetective, are provided in a new paper published in Nature Genetics titled, “Genome-scale quantification and prediction of pathogenic stop codon readthrough by small molecules.” Its developers believe that the tool could be helpful in the design, development, and efficacy of clinical...

How to harness AI’s potential in research — responsibly and ethically (www.nature.com)

The rapid growth of artificial intelligence (AI) offers immense potential for scientific advancements, but it also raises ethical concerns. AI systems can analyse vast data sets, detect patterns, optimize resource use and generate hypotheses. And they have the potential to help address global challenges including climate change,...

Saturday Citations: Tarantulas and their homies; how mosquitoes find you; black holes not mysterious at all (phys.org)

People tend to have one of two reactions to tarantulas: a sharp, primal terror that author David Foster Wallace described as “the howling fantods,” or the kind of attachment more commonly associated with kittens and puppies. People are just not indifferent to tarantulas....

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