NewPipe had to update a couple of times in the past month because YouTube made changes that broke the 3rd party playback. First time it took a few days, but so far it seems they’ve been able to keep up with YouTube’s bs.
I worry for a day when YouTube figures out how to make ads an unskippable part of the video itself so that they’re present with or without adblock, while also maintaining the ability to update them as needed.