Trans folks fall under Minorities, sorry I didn’t’t call them out by name. I can say that most people in SF don’t care. Oh sure you’ll hear someone’s old grandmother from the old country mutter something in a foreign language every blue moon, but in practice no one cares.
We have a lot of people from a lot of places that are less tolerant.
If you can drive like a fucking asshole, take 10x too long at the self checkout, and speak 5 Spanish phrases, no one will have any idea you’re from someplace else.
[edit] I’ll also add we have the nicest nude beach in all of Florida , and it is open and friendly to all and takes absolutely nothing to start a party. Just adjust to the fact that about 10% of the people will be ‘Baywatchy’, the rest are just folks, folks who may not work out, but surprisingly do an awful lot of personal grooming.