That’s a pretty broad question.
How many nodes are you running? Are you using CEPH? Or another flavour of distributed storage? Or external nas/san? Or just local arrays? Zfs? Btrfs?
What’s your backup strategy? Do you use Proxmox Backup Server?
If you can figure out what you don’t like about your current setup, there will probably be a tutorial or article about alternatives.
Sometimes they can be applied without having to reinstall (actually, 99% of them probably can. Sometimes I just find it easier to start from scratch tho)