Yeah, if you’ve got a decent amount of Linux experience, I don’t think you’ll have any issues. Mastodon’s installation is well-documented and works. My only criticism is that it’s a bit long and you have to be careful not to miss anything.
On the other hand, I recall installing Pixelfed back several months ago and having a difficult time. The documentation was lacking, and it required me to use Arch Linux, which I had never used. I was able to get it working, but eventually terminated the instance after a while because I was never using it.