mailcow lists a small german vps hoster with a fair price and the right sizing. It’s not a big hoster, gmail and microsoft are not blocking the ip-range and the ASN is not listed on any blacklist.
The support is quick and helpful, rDNS was a matter of minutes to set up. You don’t need any deeper knowlegde of docker, since it is a one-time job to set the things up und get the stack running. The documentation of mailcow is very good.
You can run it from home, but you will need a forward host like sendgrid and maybe a backup mx. You can set a primary ip and a backup ip wich will get all the mails when the primary host is down. I guess, there a comercial or free backup-mx services out there. No problem. If you have a static ip for your homelab or at least a dynamic dns-name, it will work. Recieving is easy. But you will need a good forward-service for sending.