I think the main thing is that you can get a more intense nicotine hit, probably because it is easier to smoke higher concentrations, so I assume it is more addictive in that regard. It’s a smoother smoke and you don’t get that residual nicotine in the mouth that you would at high concentrations of the freebase. You can always just try it out, most vapes are compatible with both juices, although they might be optimized for one over the other.