I wouldn’t worry too much about water availability for cooling (even though it’s an issue). I see a bigger “political” issue
A safe nuclear industry requires at laest the two following stuff
A solid academic and industrial tradition, able to train skilled engineer and technician, but also researcher to prepare the future.
A government strong enough to deal with the NIMBY, but weak enough to have an independent nuclear safety agency able to perform audits without caring about political pressure.
This works in a country like France, may still work in a country like Germany or US (even though NIMBY have more power there) but many country especially in the * third world* don’t have either trained “nuclear scientists” or a government able to guarantee nuclear safety