The US has won against guerrillas before. They won in the Philippines and had mostly won in Iraq before the Iraqi government pissed off their Sunni minority and ISIS spilled over from Syria. The US also crushed the Viet Cong during the Tet Offensive and most of the war after that was fought by regular North Vietnamese Army units not VC guerrillas.
Most insurgencies fail Max Boot wrote a book called Invisible Armies where he analyzed insurgencies throughout the 20th century and determined that only about a quarter of them succeeded and more than half failed outright. Not only that, many of the successful ones took place in the context of colonization and the Cold Warz where they had weak imperial opponents, super power backers, or both.