I really try to caution people from accepting these "it's too much to hold us accountable for" answers. If it's too much, then cut back. Simple as that. If I am a real estate mogul and my building collapses like in Miami, do you think the local/state/federal agencies involved will shrug it off when I go "Now now now, I have far too many properties. I can't possibly be expected to be in compliance all the time. A collapse and some deaths once in a while is inevitable"? Of course not, that would be ridiculous. Yet when youtube goes "we simply have too many uploads to screen it all," we do just that!
Same goes here. If you're juggling too many advertisers, why is that our problem? Hire more people, scale back, or figure out some third option. Instead we all just internalized this concept that "there's nothing that can be done."