The meme is a joke. My reply is flippant, but true.
Either way you die. Ya want your little brief window of existence to be about just getting high, or add to it creating/doing/connecting/fucking/helping/discovering/being?
You can always go with, “They’re bad for developing brains and bodies.”
The earlier you start drinking, smoking, or doing drugs the easier it is to find yourself dependant on them as you won’t develop healthy coping habits or find healthy ways to enjoy your spare time.