When developers need to draw graphics on the screen, they use an API like Direct3D (or DirectX) or Vulkan to accomplish it. Direct3D only works on Windows. Vulkan works on many operating systems. Vulkan replaced OpenGL.
DXVK translates DirectX calls, which only work on Windows, to Vulkan calls, which will work on Linux and other operating systems. It’s so good at this that it’s better than commercial game engines like Unity. DXVK is a separate project from Wine. Wine also uses wined3d to convert older Direct 3D calls to OpenGL calls, for the same effect.
Lastly, there’s VKD3D, which is Wine’s own Direct3D12 ➜ Vulkan compatibility layer. Valve forked this and created VKD3D-Proton, which is specifically designed for games, as opposed to general software.