Probably never. They’re my third option after native packages and built-from-source packages/installs either manually or using the AUR. They’re convenient and the only option I tolerate of those newer package styles (Flatpak/Snap/AppImage), but seemingly having to download a new 800+MB runtime for small 32MB applications is ridiculously wasteful and I wouldn’t touch them if I didn’t have at least a TB of storage.