Out of curiosity, what do you mean with AV software, antivirus or audio / video? If the latter is the case, check out Blender, Kdenlive, OpenShot, Flowblade, GIMP, Krita and Inkscape for graphical and video work. Pix is great for managing your photos and RawTherapee might be sufficient for your raw photo editing needs. On the audio production side, if you need a simple but powerful audio editor, look for Tenacity (a fork of Audacity). For music production, you can wonderfully work with Renoise, Reaper and Bitwig Studio natively on Linux. To make Windows VST plugins work on Linux, check out the plugin host Carla. But there are also many great linux-native VSTs out there, for example the TAL-Sampler. Great quality, free plugins are offered too, for example from calf-studio-gear.org. There are websites that list other sources.
Btw, it’s quite likely that your audio interface just works plug 'n play, if it is not too exotic. You can google that in advance though.