I’m partially disabled and stuck in a bed ~80% of my days. The ergonomics of a laptop on my custom bedside stand that can swing out of my way and 180° to use at my desk is ideal. I have a spare monitor on an arm I use when I really need it, but I hate having any regular keyboard or even being stuck with just a mouse. The touch pad, keyboard location, and screen make an ideal ergonomic situation. Like I have several mains outlets built into my stand, and the wiring is managed so that I don’t get boxed in or tangled. I hate wireless stuff going dead. When adding the cost of the screen to a PC and all the peripherals, and then accessibility mounts, it costs more for me. My only option for a tower is two computers and remotely logging in from a laptop. It is an option but not one I like.