If your concern is about the comfort using the Control key frequently, another option is to solve this at the keyboard hardware or firmware level.
For example, I use a Corne keyboard with a control key on a convenient thumb key. I also don’t have to hold it. I can tap it and tap the next key.
Also, by holding down another thumb key on the other hand, arrow keys are available for the home row. With this, using arrow keys and modifier keys via comfortable across all apps.