Most of the time it was not an issue. Occasionally a teacher gave us a office document that loaded a bit funky, but it never blocked me from doing my assignments.
Deliverables were PDFs, so it really doesn’t matter what you use.
I do remember having to learn some ghostscript command so that I could edit PDFs and stitch together a bunch of PDFs into one file. It was annoyingly difficult to edit PDFs back then, but I figured it out.