There are couple of concerns and how Fedora Workstation is designed for… well, development workstation. There is SELinux, that sometimes gets in a way, now they ditched codecs with loyalties by default, some default configs are a bit controversial and maybe not perfectly suited for home computer and non-tech savvy users, 3rd party packages are sometimes lacking and when you want to go beyond what’s in stock repo and rpmfusion, you can even break the system by installing random COPR packages (I mean AUR is not a whole lot better, but is more complete and less needed given how much there is to stock repos, PPAs are just as bad) or end up compiling stuff manually. But I still think that Fedora can be pretty nice for many people out of the box.