I can 100% back this up. I never had any issues with any of the games I play. The most effort I put in was get dotnet for assetto corsa using protontricks, and that is pretty much the only game which required tweaking from me. I mostly play metroidvanias, and all of them work for me. I can also vouch for 99% of the games out there. Warframe and csgo also work really well.