In my case here, I have a 16GBV 3080Ti paired with a 12 gen i7. The integrated graphics for the i7 are fine for all graphics operations I need. I got the GPU specifically for LLM stuff. The system memory is DDR5 and the GPU is DDR6. It is an optimus design, so it is a bit different than a desktop, but from what I’ve read, this is just a matter of thermal and power throttling features that are broken out for kernel controls that are not present in the desktop cards.
The bootloader issues are universal to all platforms that use UEFI. There are several documents available from the UEFI Consortium and NIST that cover the subject in detail and how to mitigate the problems.