So, to be clear: The idea of Leon doing that in a cutscene was theoretical. The only thing the first game had was an Easter egg triggered from looking at Ashley via low angle, which as described takes specific intentions to pull off.
Luis, a sleazy side character, does say something raunchy to her, and that was removed in the remake. It’s a little more fitting because he’s painted as untrustworthy and imperfect; but, I also realize with how many people like Ashley, it’s the sort of line that has no good response to let her be cool. In the original she just pouted “How rude!!”