C# is my primary language, so I’d certainly recommend it. It can be a little daunting to get into because it is a large ecosystem of tools, so you might want to watch some videos and keep things simple for a while.
For work I mostly use it for APIs for web sites, that might be a good place to start if you’re familiar with JS/TS front-end work. From there you might want to try Razor or Blazor for handling web UI work in C#. I’m not very experienced with that aspect of it, but it’s mostly been a positive experience (TBH I kind of prefer React, but I’d need to spend more time on the Razor/Blazor side to have a strong opinion).
The desktop development side in C# is kind of a mess at the moment. Maybe stick with web until you’re feeling pretty comfortable with the language.