When searing meat and adding spice in a more or less "dry way", for taco meat or chili or some curries, I sear the meat to nearly where I want it, then add the dry spices to toast on lower heat before "deglazing" with water/stock/whatever else makes sense. You can also just toast the spices separately, but some toasting is nice either way and I think this is convenient.
Generally salting early is good for anything you want to get any kind of browning on, it's just that the meat and any other additions might also be salty, so you don't always get to. Spices will give a better flavor over time, like a "rub", but you can't necessarily sear meat with spices on it. Things are usually tradeoffs.