So as far as bike fit and road, if a road bike is fit properly, you won’t have weight on your wrists or hands. It probably sounds a little unintuitive, but a proper bike fit on road is all about balancing your weight so that your upper body is neutral without any weight on your arms. Like, the primary test to see if your saddle position is correct is to see if you can pedal smoothly on a trainer while taking your hands off the bars completely.
The key here is that the centerline of the crank arms is the fulcrum of the rider’s balance. The adjustment of this balance point is set by sliding the seat fore and aft, thus placing more or less of the rider’s posterior to the rear of center.
The only reason I can still ride is because my thoracic (spine section where the ribs are attached) is neutral when I ride, which by inference also means my arms must be neutral too.
I am totally fine with people that don’t wish to try it or cycle for whatever reason. I’m simply trying to relate that road bikes are not like any other kind of bike. They are intended to be fine tuned to one’s anatomy, and this makes it possible to ride even when many other forms of exercise are not possible. I can’t swim or do anything sitting upright, standing, or reaching, yet can ride. GL. I wish you the best.