Knew someone like this, took a while to learn how unhealthy it is. Politely call it out by asking “This seems to really be bothering you and I don’t want to be doing that to you. What’s actually wrong here?”
For many, it’s amazing how quickly behaviors can change when they realize they can be straight forward without a negative reaction.
Edit: Supportive can be the best reaction in most situations. Home, work, etc. As long as it doesn’t harm your own mental or physical health, and that you also get what you need.