Binging with Babish - the content just drifted away. He started doing a show with another guy and I just didn't watch those episodes. Then, the content went further and I stopped watching.
Joshua Weissman - he just became insufferable at some point. I liked his older content.
Shadiversity, Sabine Hossenfelder - they have positions that cause hurt to people and that I morally do not agree with and won't give watch time or ad/sub money to. There are probably more here, but I don't recall. They're welcome to their opinions, but I'm not entitled to view them or fund them.
First we Feast - mostly watched it for Hot Ones (the Motz's stuff was fantastic!) but I got tired of Hot Ones, didn't know most of the guests for a long stretch (not living in the US or really consuming US media made me lose track of things). I also kinda got burnt out on the format.
Linus Tech Tips - to me, it just became the arrogant, egotistical Linus show. There was some other stuff that kinda put me off as well. Maybe it's better now, but I haven't watched in a long while at this point.
A number of creators I'm not thinking of - I hate when prescription meds are advertised (which isn't even legal in the vast majority of countries) and how they just want to sell dick pills without a real, non-conflict-of-interest doctor involved when the cause may not even be physical. I worked in healthcare for a long time and that just rubbed me the wrong way, particularly when creators in countries where it would be illegal for them on TV do it (and it may not even be legal/available in their country but it is in the country of at least US-based audience members).
Edit: and the 8-bit guy now, based on others mentioning things, checking other sources, and even checking up a follow-up video he made a year ago. I'll pass.