I think people are far too concerned with airplane seating. Concerning boarding: The plane takes off at exactly the same time, whether you’re the first or the last person entering it. And upon arriving, the people are way quicker leaving. It’s maybe a difference of 3-10 minutes. This might matter if you’re in a hurry or want to be the first person in the customs line. I like to stay relaxed when travelling.
The noises are everywhere. There might be a minor difference and it probably really depends on the airplane model. The slight vibrations, engine noises and air-con noises are audible from front to the back. At least that’s my observation. Most annoying thing I had happen is a crying and vomiting 5-year-old in the row next to me. But I don’t think there is much you can do about that. I’ve sat right over the wings and it’s fine. And I think I’ve read those are better concerning safety, but you don’t need to worry about safety too much.