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bbc.co.uk

The_v , to world in Cystic fibrosis: The miracle drugs priced out of reach

Just some basics about the company.

Revenue Income US$8.93 billion (2022)

Operating income US$4.31 billion (2022)

Net income US$3.32 billion (2022)

The bulk of the difference between operating income and net income in a research driven company is the R&D. They are running at 11% just under $1 billion per year. A publically traded company can’t really hide their research costs, only obscure it for the uniformed.

Their net income is 37% of revenue. So they are paying for over 4 years of research for every year (3 past years plus current gear). So their argument they need the high prices to cover past research costs is pure bullshit. I’d give them the current year and one past year. But 4 years?

This is pure price gouging for profit over people’s lives. Invalidating their patent is fully justified.

knotthatone , to worldnews in IOC boss says individual athletes cannot be punished for acts of their governments, defending move to allow Russians and Belarusians to compete as neutrals

I agree with this in principle, but the way they were allowed to compete as the “Russian Olympic Committee” was bullshit. You can’t have a team called “totally not Russia (wink)” and expect that to be a meaningful punishment for the nations leaders

I think the athletes should only be able to compete as citizens of the world with no reference or acknowledgement of the banned country allowed.

realharo ,

That will never work as long as they’re the only country in that situation. They would need to be mixed with athletes from other unrelated countries for this to make sense.

PrinceWith999Enemies ,

The point isn’t to disguise them. The point is to call attention to their country’s misdeeds by refusing them the honor of flying their colors. Perhaps the individual athletes should still win medals, but the IOC wouldn’t assign the credit to Russia, who would not be eligible for them.

Armen12 , to worldnews in IOC boss says individual athletes cannot be punished for acts of their governments, defending move to allow Russians and Belarusians to compete as neutrals

He’s right, blaming the innocent civilians for something a dictator does is morally and ethically wrong. Germany had to go through all of this before. Other countries guilty of genocide are allowed in the Olympics like China, which is one of the worst offenders and cheats every single time, so why are they allowed?

theodewere , to news in Alexei Navalny: Russian opposition leader's whereabouts are unknown
@theodewere@kbin.social avatar

just like Prigozhin, this guy scares the SHIT out of Putin

eran_morad , (edited ) to news in Alexei Navalny: Russian opposition leader's whereabouts are unknown

He’ll be confirmed dead by some bureaucrat or “doctor” in a few weeks’ time, tops.

Chainweasel , to news in Alexei Navalny: Russian opposition leader's whereabouts are unknown

This will be every well known Democrat in the US if Trump wins in 2024. Joe Biden, Hillary Clinton, AOC, Bernie Sanders, etc. If you’ve heard their name they’ll be in a labor camp before the end of 2025 if Trump wins.

FlyingSquid ,
@FlyingSquid@lemmy.world avatar

Bold of you to think they’ll be alive long enough to do any labor in those camps.

The camps are for us little people to keep the economy going.

autotldr Bot , to world in Cystic fibrosis: The miracle drugs priced out of reach

This is the best summary I could come up with:


In February, legal papers were filed with the South African High Court, seeking a compulsory licence that would allow the supply of more affordable generic versions of the CF drug.

Research led by Dr Andrew Hill, of the University of Liverpool pharmacology department, found the basic production cost for these drugs was less than $6,000 (£4,790) a year per patient.

The government began discussing invoking what is known as a Crown use licence, which would have swept aside the company’s exclusivity rights to these drugs and allowed the UK to buy in generic, vastly cheaper versions of the treatment.

But some patients, desperate for access to these drugs in the meantime, took matters into their own hands and created a buyers club, flying to Argentina to buy a generic version produced by a company there.

And these results were published before the announcement the UK Medicines and Healthcare products Regulatory Agency had extended the licences of Kaftrio and Kalydeco to two- to five-year-olds, which will increase the amounts needed for NHS patients.

The second NICE committee meeting to discuss the comments submitted during the consultation period is on Thursday, with a final recommendation regarding NHS funding for these treatments expected next spring.


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Squizzy , to worldnews in IOC boss says individual athletes cannot be punished for acts of their governments, defending move to allow Russians and Belarusians to compete as neutrals

The Russians have been cheating for how long anyway!? I’d never trust a win from them. Olympics is shite now

Tosti , to worldnews in IOC boss says individual athletes cannot be punished for acts of their governments, defending move to allow Russians and Belarusians to compete as neutrals
@Tosti@feddit.nl avatar

He is wrong though. And this a-political stance is the opposite of why the Olympics was started. Fight in sports not on the battlefield!

Vilian ,

exactly, these countries take pride when winning, no more pride for them,ç

brain_in_a_box ,

Wait, are you saying he’s wrong and that individuals should be punished for acts of their government?

Tosti ,
@Tosti@feddit.nl avatar

Well, you can really zoom in on the individual, and decide. But if the person is in the military, or completely on the Russian government’s dime, they are spokespeople for that government. That government is not welcome, by extension the athlestes are not welcome. The olympics should not be a platform for idols of the russian federation to gain a platform.

brain_in_a_box ,

Will that standard be applied consistently? Will USA athletes be punished for the acts of their government? British? Saudi? Isreali?

Because it not, it becomes clear that this has nothing to do with principles and everything to do with politics.

Tosti ,
@Tosti@feddit.nl avatar
brain_in_a_box ,

Err, no. All countries should be held to an equivalent standard.

autotldr Bot , to worldnews in IOC boss says individual athletes cannot be punished for acts of their governments, defending move to allow Russians and Belarusians to compete as neutrals

This is the best summary I could come up with:


Last week, the IOC said individual athletes from Russia and and its ally Belarus who had qualified for the Paris summer games would be allowed to compete without flags, emblems or anthems of their countries.

Mr Bach was speaking exclusively to the BBC at the UN Global Refugee Forum in Geneva on Wednesday.

Olympic sports federations had asked the IOC to allow Russian and Belarusian athletes to compete but with no affiliation to their nations.

This was despite a number of countries - including the US and UK - calling for an all-out ban amid the ongoing war in Ukraine.

Ukraine itself suggested it might boycott the games, with President Volodomyr Zelensky saying Russian athletes “cannot be covered up with some pretended neutrality.”

Mr Bach dismissed the threats of a boycott, saying countries that disagree “are allowed to have different political opinions”.


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autotldr Bot , to world in Wales' First Minister Mark Drakeford resigns

This is the best summary I could come up with:


Mark Drakeford has announced he will stand down as Welsh Labour leader immediately and a leadership contest for a new first minister will be held.

A new party leader will be elected before Easter, Mr Drakeford said in a statement.

Mr Drakeford, 69, the Cardiff West Member of the Senedd (MS), has been first minister for five years.

Speaking at a hastily arranged press conference in the Welsh Parliament, Mr Drakeford said: "When I stood for the leadership, I said that, if elected, I would serve for five years.

This breaking news story is being updated and more details will be published shortly.

You can receive Breaking News on a smartphone or tablet via the BBC App.


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autotldr Bot , to world in Kenya's nationwide power blackout sparks KPLC sabotage suspicions

This is the best summary I could come up with:


A power blackout that plunged Kenya into darkness on Sunday was a possible act of sabotage, a minister says.

The outage disrupted several services, including the main airport in the capital, Nairobi, where two terminals were without power for several hours.

“Considering the frequency of the power disruption, and taking into account the fact that JKIA is a facility of strategic national importance, we are making a formal request to the National Police Service to investigate possible acts of sabotage and coverup,” he posted on X.

In its most recent update, Kenya Power said it was “working round the clock to restore normalcy to the remaining areas as soon as possible”.

Energy Minister Davis Chirchir has attributed the outage to a powerline overload, which then caused a failure to the country’s entire power network.

The government will also build additional networks over the next 20 months to relieve the currently overloaded transmission lines and prevent future outages, Mr Chirchir added.


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autotldr Bot , to world in Elite Afghan troops face return to Taliban after UK 'betrayal'

This is the best summary I could come up with:


Gen Sir Richard Barrons, who served the British Army in Afghanistan over 12 years, told BBC Newsnight that the failure of the UK to relocate these soldiers “is a disgrace, because it reflects that either we’re duplicitous as a nation or incompetent”.

In 2021, Prime Minister Boris Johnson had told Parliament that the service of these Afghan special forces had been “incredibly important”, adding the UK would do “whatever we can” to get “safe passage” for them.

The BBC has obtained a private letter sent in March 2022 to the Foreign Office, which called for urgent help to be given to a group of 32 former governors, prosecutors and officials who worked with the UK and US in Helmand Province during operations between 2006 and 2014.

“Ali”, one of the Afghan special forces soldiers facing expulsion from Pakistan, told the BBC he felt abandoned and betrayed by the UK.

The estimated figures suggesting there are about 200 commandos like Ali facing deportation by the end of the year have been gathered through a secret network of former members of Afghan security forces and given to the BBC.

One time, he wrapped his arms around a would-be suicide bomber, preventing him from detonating his explosive vest and likely saving dozens of lives, including women and children.


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e_mc2 , to worldnews in The Israelis grappling with helping sick Palestinians

This is a very little uplifting news in the otherwise immensely sad dystopian reality that is Gaza right now. Fortunately there are still some people who actively show some humanity over there.

autotldr Bot , to worldnews in The Israelis grappling with helping sick Palestinians

This is the best summary I could come up with:


Yael Noy doesn’t wear military fatigues, but she describes herself as being in battle right now, after the Hamas assault on 7 October.

Yael heads a charity called Road to Recovery, a group of Israeli volunteers who drive sick Palestinians - mostly children - from checkpoints in the occupied West Bank and Gaza to hospital appointments in Israel.

They include Vivian Silver, a renowned peace activist; Adi Dagan, who Yael describes as “funny” and always ready to step in and ferry patients at short notice in his big car; Tammy Suchman, a much-loved grandmother; and Eli Or-Gad, who loved talking about poetry.

She and most of the Road to Recovery volunteers have continued to drive Palestinians from the West Bank to hospitals in Israel for cancer treatment, organ transplants and kidney dialysis.

Yael is also desperately concerned for two Road to Recovery volunteers, Oded Lifschitz and Chaim Peri, who are still being held hostage by Hamas.

Since 7 October, some Road to Recovery’s volunteers have dropped out of driving altogether or decided to focus on taking medicines to displaced Israelis instead, while the war lasts.


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