OK, let’s assume for the sake of the argument that everything you just said is 100% correct. Why aren’t you also saying Dave Chapelle is a pedophile, or a racist, or a homophobe? Children, racial minorities, and gay men are all other groups he made jokes about and they all fit your criteria of “people at danger in our society”.
The fact that transphobic is the only descriptor I hear about that show suggests to me that this is not really the criteria you’re using to evaluate the situation, it’s merely convenient cover to give when pressed that will pacify most people. At minimum it means you’re giving those other comments a pass as jokes and choosing not to do so with his trans jokes and that is absolutely inconsistent no matter how you try and spin it.