Look at all those healthcare companies. Fifty years ago, such a list might have a Big Pharma company, but no patient care portals at all (hospitals, pharmacies, etc). Now they dominate the whole list.
And it’s also worth noting that several of these are also huge players in the opioid crisis, including the four who settled to avoid state lawsuits that would have gutted them (looking at you Cencora, McKesson, Johnson&Johnson, and Cardinal Health).