From the brief Google searching I’ve done it appears to be possible, though, I’m not sure if proxmox skills will help me professionally. I used VMware before because I needed to learn VMware esxi and vcenter. I know it fairly well at this point.
I want to target a hypervisor solution used in large companies, I’m not sure that’s proxmox. Currently I’m leaning towards OpenStack, since I know some cloud providers use it for VPS offerings. I know enough about hyper-V that I know I don’t want to use it, ever. At least outside the context of Azure VMs. I can’t really do Azure cloud at home (they’re is a way, I’ve looked into it, but it’s very expensive), though my current workplace uses Azure extensively.
I’m just not aware of any company using proxmox as a VM platform, whether single host or clustered.